Autotitrator

The figure on the right shows a screenshot of the results from our autotitrator, the Titraumatic. There is a video demonstrating some features of the software below the figure.

The Titraumatic incorporates our syringe pump and a Vernier Instruments  pH probe.  It is controlled from your computer using a Texas Instruments Tiva LaunchPad microntroller board and an open-source user interface.   We began developing this instrument to run titration demonstrations for our university level freshman chemistry class.  The titraumatic allows the instructor to run a pH titration while lecturing and to project the results for the class in real time.  In contrast to a typical end-point titration, presenting the entire titration curve can be used to introduce the students to the effects of added base (or acid) outside of the end point range.  That is, it can be used to teach about equilibrium, or buffers, or acid / base strengths. 

While the instrument is still under development, you can see from our initial results that the instrument shows promise.  We anticipate having the instrument ready for market in the summer of 2017. 

Hardware Requirements:

The circuit board layout for our syringe pump / auto titrator is compatible for use in our autotitrator with minimal modification.  In addition to a Brittish Telecommunications Analog (BTA) connector for the pH probe, the titrator circuit board incorporates a voltage regulator and connectors needed to control an automated valve.   If you wish to use your pump as an autotitrator, please contact us before ordering. 

In addition to our Syringe Pump, you will need a Vernier Instruments pH probe (see link on right for Vernier Instruments).  At the time I wrote this, the pH probe retailed for $80.  While it is entirely possible to run titrations with out the automatic valve, this feature allows the user to set up to automate the fill / dispense features.  The automated valve assembly uses a valve from Hamilton Co (costs ~$80), a servo (~$14) and some 3D printed hardware.  Instructions for assembling the Titraumatic kit are provided here.

View Cart: (0)‏
WHAT'S UP?

CURRENT PROJECTs

 

August 2020:

  Work during summer 2020 focused on the WheeTrometer spectrometer and on the WheeStat potentiostat.

  The spectrometer is coming along.  We are currently working to improve the intensity resolution by adopting a high resolution analog to digital converter.

  Our work on the WheeStat is focused mostly on increasing the current output available.  In addition, we hope to increase the range of frequencies that can be obtained by adding a digital to analog converter.

August, 2017:

   Work during summer 2017 focused on two projects, the WheeStat potentiostat and the stopped flow spectrometry apparatus.

  •    Work on the WheeStat included changes to the user interface, firmware and hardware.  The newest version of the user interface, WheeStat6.0c, has a new zoom feature and a few bugs from the older interface have been fixed.  We believe the new hardware will be out by the end of 2017.  The new hardware will have an improved method for turning off applied voltatage between experiments.  This is a hardware fix that requires modification of the firmware as well.  We will offer an add-on for our earlier hardware versions that incorporates this feature.  Addditional changes include increased current ranges and the potential for significantly increased scan rates.

  • Work on the stopped flow spectrometry project focused on increasing the injection speed.  Our initial effort focused on developing a rack and pinnion drive for the syringes.  This improved injection speed relative to the lead screw drive but failed to meet target speeds due, we believe, to limited torque provided by the small NEMA 17 motors we chose.  Our next attempt employed larger NEMA 23 motors.  These have significantly higher torque.  Unfortunately, our flow cell was unable to contain the generated pressure and began leaking.  Current efforts are focused on developing a lab-built UV-vis cell that will hold higher pressures.

 

September, 2016:

  • Our work to automate solid phase synthesis of peptides / DNA, etc has progressed well, although the chemistry is more involved that I had origianally thought.  We have made our first attempt at synthesis of a cystiene modified tri-peptide

  • Our application for recognition by the IRS as tax exempt under 501(c)3 has been approved.

  • We have begun work on a low cost visible spectrometer that will use home built reflective optics.

  • We are working on developing a stopped flow kinetics instrument based on commercially avialable spectrometer.  Our current prototype is able to acquire spectra within 120 ms of mixing.  This dead time appears to be limited by the power of the motors we used.  We are investigating the use of larger motors and hope to get the dead time down to below 12 ms.

 

EVENTs

6-10

PITTCON CONFERENCE & EXPO 2016

 

Presentation  in Atlanta, GA,  March 6-10, 2016

Our talk was well recieved at the Educational symposium at PittCon

CONTACT

4989 Tilley Creek Road

Cullowhee, NC 28723

Tel: 828-293-7781
 

 

Mail:  summers@wcu.edu

j6summers@gmail.com

  • w-facebook
  • Twitter Clean
  • w-googleplus

21

2016 SE REGIONAL ACS MEETING

Oct 23-27, SouthEast Regional Meeting of the American Chemical Society, Columbia SC

© 2015 by Smoky Mt Scientific. PROUDLY MADE BY WIX.COM